SHARe: SNP Health Association Resource

Program Description

The NHLBI SHARe Project will conduct genome wide association studies and analyses in several large NHLBI Cohort studies to identify genes underlying cardiovascular and lung disease and other disorders like osteoporosis and diabetes. The first SHARe cohort is the Framingham Heart Study, in which genotyping of 550,000 SNPs has been completed in over 9,000 subjects from three generations. The second cohort is the SHARe Asthma Resource Project (SHARP), which includes genotyping data from adults and children who have participated in NHLBI clinical research trials on asthma. The NIH National Center for Biotechnology Information is developing and housing the database for this research project in its Database for Genotype and Phenotype (dbGaP). Data will be are available at no cost to all qualified investigators via an application process involving an NHLBI Data Access Committee. Further details as well as the application can be found at the related website below.

The NHLBI Program Officers for SHARE are Christopher O’Donnell, MD, MPH (Scientific Director) and Phyliss Sholinsky, M.S.P.H.

Related Websites:

NHLBI Whole Genome Association at NCBI

Program Start and End Date

April 2006 to October 2009

Original Funding Announcement (FOA)

SNP Health Association Resource (SHARe)
NHLBI-PB-2006-091